Search on: TRANSCRIPTION FACTOR, ATF6 
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Descriptor English:   Activating Transcription Factor 6 
Descriptor Spanish:   Factor de Transcripción Activador 6 
Descriptor Portuguese:   Fator 6 Ativador da Transcrição 
Synonyms English:   ATF6 Transcription Factor
Transcription Factor, ATF6  
Tree Number:   D12.644.360.011
D12.776.260.108.061.968
D12.776.476.011
D12.776.930.127.061.968
Definition English:   One of the BASIC-LEUCINE ZIPPER TRANSCRIPTION FACTORS that is synthesized as a membrane-bound protein in the ENDOPLASMIC RETICULUM. In response to endoplasmic reticulum stress it translocates to the GOLGI APPARATUS. It is activated by PROTEASES and then moves to the CELL NUCLEUS to regulate GENETIC TRANSCRIPTION of GENES involved in the unfolded protein response. 
History Note English:   2006(1997) 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification DF deficiency
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   50762 
Unique Identifier:   D051702 

Occurrence in VHL:
 

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